Estriol

MeSH ID: D004964

DEFINITION: A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.

Related Concepts:

• Estriol [M0007788]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Steroid [T110]
  • Hormone [T125]
  Concept Terms:
  • Estriol [T015148]
  • 16 alpha Hydroxy Estradiol [T526121]
  • 16 Hydroxyestradiol [T015147]
• Ovestin [M0007790]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Steroid [T110]
  • Hormone [T125]
  Concept Terms:
  • Ovestin [T015151]
• Epiestriol [M0450178]
  Concept Semantic Types:
  • Steroid [T110]
  Concept Terms:
  • Epiestriol [T542697]
• 17-Epiestriol [M0330345]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Steroid [T110]
  • Hormone [T125]
  Concept Terms:
  • 17 Epiestriol [T360539]
• 16-Epiestriol [M0007789]
  The 16 beta-isomer of ESTRIOL.
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Steroid [T110]
  • Hormone [T125]
  Concept Terms:
  • 16 Epiestriol [T015150]
• 16,17-Epiestriol [M0330347]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Steroid [T110]
  • Hormone [T125]
  Concept Terms:
  • 16,17 Epiestriol [T360541]

Qualifiers:

administration & dosage [Q000008] ; adverse effects [Q000009] ; agonists [Q000819] ; analogs & derivatives [Q000031] ; analysis [Q000032] ; antagonists & inhibitors [Q000037] ; biosynthesis [Q000096] ; blood [Q000097] ; cerebrospinal fluid [Q000134] ; chemical synthesis [Q000138] ; chemistry [Q000737] ; classification [Q000145] ; contraindications [Q000744] ; deficiency [Q000172] ; diagnostic use [Q000176] ; economics [Q000191] ; genetics [Q000235] ; history [Q000266] ; immunology [Q000276] ; isolation & purification [Q000302] ; metabolism [Q000378] ; pharmacokinetics [Q000493] ; pharmacology [Q000494] ; physiology [Q000502] ; poisoning [Q000506] ; radiation effects [Q000528] ; secretion [Q000557] ; standards [Q000592] ; supply & distribution [Q000600] ; therapeutic use [Q000627] ; toxicity [Q000633] ; urine [Q000652]

Tree Structure:

• Chemicals and Drugs [D ]
  • Polycyclic Compounds [D04 , D011083]
    • Steroids [D04.808 , D013256]
      • Estranes [D04.808.365 , D004962]
        • Estrenes [D04.808.365.415 , D004963]
          • Estriol [D04.808.365.415.331, D004964]
            • Estetrol [D04.808.365.415.331.320, D004953]

• Chemicals and Drugs [D ]
  • Hormones, Hormone Substitutes, and Hormone Antagonists [D06 , D006730]
    • Hormones [D06.472 , D006728]
      • Gonadal Hormones [D06.472.334 , D042341]
        • Gonadal Steroid Hormones [D06.472.334.851 , D012739]
          • Estradiol Congeners [D06.472.334.851.437 , D045166]
            • Estriol [D06.472.334.851.437.750, D004964]
              • Estetrol [D06.472.334.851.437.750.320, D004953]

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