MeSH
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Floxuridine

MeSH ID: D005467

DEFINITION: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

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Qualifiers:

administration & dosage [Q000008] ; adverse effects [Q000009] ; agonists [Q000819] ; analogs & derivatives [Q000031] ; analysis [Q000032] ; antagonists & inhibitors [Q000037] ; blood [Q000097] ; cerebrospinal fluid [Q000134] ; chemical synthesis [Q000138] ; chemistry [Q000737] ; classification [Q000145] ; contraindications [Q000744] ; diagnostic use [Q000176] ; economics [Q000191] ; history [Q000266] ; immunology [Q000276] ; isolation & purification [Q000302] ; metabolism [Q000378] ; pharmacokinetics [Q000493] ; pharmacology [Q000494] ; poisoning [Q000506] ; radiation effects [Q000528] ; standards [Q000592] ; supply & distribution [Q000600] ; therapeutic use [Q000627] ; toxicity [Q000633] ; urine [Q000652]

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