Androstenediol

MeSH ID: D015114

DEFINITION: An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-HYDROXYSTEROID DEHYDROGENASES).

Related Concepts:

• Androstenediol [M0023251]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Steroid [T110]
  • Biologically Active Substance [T123]
  Concept Terms:
  • Androstenediol [T044153]
  • 5 Androstene 3,17 diol [T044151]
  • 5 Androstene 3beta 17beta Diol [T044147]
  • Androst 5 ene 3 beta,17 beta Diol [T044148]
  • Androst 5 ene 3,17 diol [T044152]
  • delta 5 Androstene 3 beta,17 beta Diol [T044149]
  • Delta 5 Androstenediol [T044154]
  • Hermaphrodiol [T044150]
• Bisexovister [M0433954]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Steroid [T110]
  Concept Terms:
  • Bisexovister [T509139]
  • Parke Davis Brand of Androstenediol [T509140]

Qualifiers:

administration & dosage [Q000008] ; adverse effects [Q000009] ; agonists [Q000819] ; analogs & derivatives [Q000031] ; analysis [Q000032] ; antagonists & inhibitors [Q000037] ; blood [Q000097] ; cerebrospinal fluid [Q000134] ; chemical synthesis [Q000138] ; chemistry [Q000737] ; classification [Q000145] ; contraindications [Q000744] ; diagnostic use [Q000176] ; economics [Q000191] ; history [Q000266] ; immunology [Q000276] ; isolation & purification [Q000302] ; metabolism [Q000378] ; pharmacokinetics [Q000493] ; pharmacology [Q000494] ; poisoning [Q000506] ; radiation effects [Q000528] ; standards [Q000592] ; supply & distribution [Q000600] ; therapeutic use [Q000627] ; toxicity [Q000633] ; urine [Q000652]

Tree Structure:

• Chemicals and Drugs [D ]
  • Polycyclic Compounds [D04 , D011083]
    • Steroids [D04.808 , D013256]
      • Androstanes [D04.808.054 , D000731]
        • Androstenes [D04.808.054.079 , D000736]
          • Androstenols [D04.808.054.079.429 , D000737]
            • Androstenediols [D04.808.054.079.429.154 , D000734]
              • Androstenediol [D04.808.054.079.429.154.050, D015114]

• Chemicals and Drugs [D ]
  • Hormones, Hormone Substitutes, and Hormone Antagonists [D06 , D006730]
    • Hormones [D06.472 , D006728]
      • Gonadal Hormones [D06.472.334 , D042341]
        • Gonadal Steroid Hormones [D06.472.334.851 , D012739]
          • Testosterone Congeners [D06.472.334.851.968 , D045165]
            • Androstenediol [D06.472.334.851.968.750, D015114]

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