Misoprostol

MeSH ID: D016595

DEFINITION: A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective anti-ulcer agent and also has oxytocic properties.

Related Concepts:

• Misoprostol [M0025309]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Misoprostol [T049700]
• Novo-Misoprostol [M0474347]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Novo Misoprostol [T614550]
  • Misoprostol Novopharm Brand [T614551]
• Glefos [M0474346]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Glefos [T614548]
  • Misoprostol Grunenthal Brand [T614549]
• SC-30249 [M0025310]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • SC30249 [T049702]
• SC-29333 [M0352609]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • SC29333 [T049701]
• Misoprostol, (11beta,13E,16S)-Isomer [M0329469]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Misoprostol, (11beta,13E,16S)-Isomer [T359663]
• Misoprostol, (11beta,13E,16R)-Isomer [M0329470]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Misoprostol, (11beta,13E,16R)-Isomer [T359664]
• Misoprostol, (11beta,13E)-(+-)-Isomer [M0329465]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Misoprostol, (11beta,13E)-(+-)-Isomer [T359659]
• Misoprostol, (11alpha.13E,16S)-Isomer [M0329468]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Misoprostol, (11alpha.13E,16S)-Isomer [T359662]
• Misoprostol, (11alpha,13Z)-(+-)-Isomer [M0329466]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Misoprostol, (11alpha,13Z)-(+-)-Isomer [T359660]
• Misoprostol, (11alpha,13E,16R)-Isomer [M0329467]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Misoprostol, (11alpha,13E,16R)-Isomer [T359661]
• Misoprostol, (11alpha,13E)-Isomer [M0329471]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Misoprostol, (11alpha,13E)-Isomer [T359665]
• Cytotec [M0025311]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Cytotec [T049703]
  • Misoprostol Heumann Brand [T614542]
  • Misoprostol Pharmacia Brand [T614543]
  • Pharmacia Spain Brand of Misoprostol [T614544]
  • Misoprostol Searle Brand [T614545]
• Apo-Misoprostol [M0474345]
  Concept Semantic Types:
  • Pharmacologic Substance [T121]
  • Eicosanoid [T111]
  Concept Terms:
  • Apo Misoprostol [T614546]
  • Misoprostol Apotex Brand [T614547]

Qualifiers:

administration & dosage [Q000008] ; adverse effects [Q000009] ; agonists [Q000819] ; analogs & derivatives [Q000031] ; analysis [Q000032] ; antagonists & inhibitors [Q000037] ; blood [Q000097] ; cerebrospinal fluid [Q000134] ; chemical synthesis [Q000138] ; chemistry [Q000737] ; classification [Q000145] ; contraindications [Q000744] ; diagnostic use [Q000176] ; economics [Q000191] ; history [Q000266] ; immunology [Q000276] ; isolation & purification [Q000302] ; metabolism [Q000378] ; pharmacokinetics [Q000493] ; pharmacology [Q000494] ; poisoning [Q000506] ; radiation effects [Q000528] ; standards [Q000592] ; supply & distribution [Q000600] ; therapeutic use [Q000627] ; toxicity [Q000633] ; urine [Q000652]

Tree Structure:

• Chemicals and Drugs [D ]
  • Lipids [D10 , D008055]
    • Fatty Acids [D10.251 , D005227]
      • Fatty Acids, Unsaturated [D10.251.355 , D005231]
        • Eicosanoids [D10.251.355.255 , D015777]
          • Prostaglandins [D10.251.355.255.550 , D011453]
            • Prostaglandins, Synthetic [D10.251.355.255.550.700 , D011465]
              • Prostaglandins E, Synthetic [D10.251.355.255.550.700.450 , D011459]
                • Misoprostol [D10.251.355.255.550.700.450.500, D016595]

• Chemicals and Drugs [D ]
  • Biological Factors [D23 , D001685]
    • Inflammation Mediators [D23.469 , D018836]
      • Prostaglandins, Synthetic [D23.469.700 , D011465]
        • Prostaglandins E, Synthetic [D23.469.700.660 , D011459]
          • Misoprostol [D23.469.700.660.500, D016595]

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